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Home |  RNAi | Thermo Scientific Open Biosyst | Thermo Scientific Open Bio (3) | Druggable Genes focused sub-li
Druggable Pie Chart


Purchasing Information
Cat # Description Literature ACA COM Buy
RHS5151
 Hs GIPZ druggable genes shRNAmir focused sub-library-Glycerol   call call
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(only clones from RHS5151)
RMM5204 Mm GIPZ druggable genes shRNAmir focused sub-library-Glycerol   call call
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(only clones from RMM5204)
RHS5196
 Hs pSM2 druggable genes shRNAmir focused sub-library-Glycerol   call call
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(only clones from RHS5196)
RMM5203 Mm pSM2 druggable genes shRNAmir focused sub-library-Glycerol   call call
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(only clones from RMM5203)
RHS4332
 Hs TRC druggable genes shRNAmir focused sub-library-Glycerol   call call
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(only clones from RHS4332)
RMM4558 Mm TRC druggable genes shRNAmir focused sub-library-Glycerol   call call
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(only clones from RMM4558)
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Druggable Genes focused sub-libraries
targeting genes with theraputic potential
The Druggable genes focused sub-library includes shRNA targeting genes that are considered potential targets for therapeutics (1,2). These include genes from the following gene families:
  • GPCR
  • Protein Kinases
  • Ion Channels
  • Phosphatases
  • Proteases
  • Ubiquitin Conjugation 1 - Cullins, E1, E2, HECT E3 Ligases
  • Ubiquitin Conjugation 2 - F-box, SOCS box E3 Ligases
  • Ubiquitin Conjugation 3 - RING finger and RING finger-like E3 Ligases
  • Published Drug Targets
Druggable genes focused sub-libraries have been created from the pSM2 retroviral, pGIPZ lentiviral  and the pLKo.1 lentiviral  libraries.

Download the individual product data sheet and data file from the purchase grid for additional details.

HumanpGIPZpSM2TRC
Genes 7,0637,2277,349
Constructs20,54023,99939,627

MousepGIPZpSM2TRC
Genes6,233
6,305
6,800
Contructs14,34715,69435,728
 
Shipping Information:
GIPZ lentiviral shRNAmir gene families and pathway rearrays are provided in 96-well microtiter plates containing frozen stock cultures of E.coli in LB (low salt) broth with 8% glycerol, carbenicillin (100ug/ml) and zeocin (25ug/ml).
pSM2 retroviral shRNAmir gene families and pathway rearrays are provided in 96-well microtiter plates containing frozen stock cultures of E.coli in (DH10bpir116) in 2XLB broth with 8% glycerol, chloramphenicol (25ug/ml),  and kanamycin (25ug/ml). 
TRC lentiviral shRNA gene families and pathway rearrays are provided in 96-well microtiter plates containing frozen stock cultures of E.coli in 2XLB broth with 8% glycerol, carbenicillin (100ug/ml).

Open Biosystems checks all cultures for growth prior to shipment. Store at -80ºC.

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